Left atrial volumes evaluation by cardiac magnetic resonance - time to revise the grading severity cut off values

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): This work was supported by a grant Ministery Research and Innovation, CNCS-UEFISCDI, project number 5/2018 83/2018 PN-III-P1-1-TE-2016-0669, within PNCDI III Background Left atrial maximal volume (LAVmax) assessed 2D echocardiography (2DE) is incorporated in new scoring system (2019) heart failure with preserved ejection fraction (HFpEF), using well established cut-off values for grading severity. These have strong evidence diagnosis prognosis. Moreover, cardiac magnetic resonance (CMR) also included the structural evaluation HFpEF. However, LAVmax evaluated CMR are higher. might generate different classification LA dilation CMR, potentially including patients another risk class. We aimed to evaluate LAVi 2DE group HFpEF patients, order test agreement between these two methods, regarding severity grading. Methods. prospectively enrolled 74 (68 ± 9 yrs), them CMR. Conventional used define anatomy function left ventricle (LV). NTproBNP done all patients. biplane index (LAVimax) minimal (LAVimin), from 4C 2C views, reported as mean value, eco (area–length method). Cohen"s k determine if there an cut off LAVimax eco, provided guidelines (Figure) Results. Feasibility complete analysis 95% (70 pts). LVEF 60 5.7%. LAVimin were highly correlated (all R > 0.7, p < 0.001) (Table). diagnosed high percent having normal values, comparison echo (59 vs. 5.7 %, (Figure). There no methods (Cohen"s = 0.000), suggesting that provides completely significantly only (R 0.4, 0.04). Conclusions. suggest need future update cut-offs LAV larger reference range studies, prognosis already provided. The present misclassification certain pathological condition, such min, instead max should be study assessment volumes ECO (ml/m2) 47 11 23 51 15 26 12 coefficient 0.7 0.74 P value <0.001 Figure.